The European Society of Anaesthesiology and Intensive Care has endorsed PROtective VEntilation Network (PROVENet) initiated by a group of preclinical and clinical investigators to perform multicenter clinical studies, randomized controlled trials, and meta-analyses. PROVENet was established following several smaller single–centre and multicenter investigations into potential protective effects of certain mechanical ventilation settings and/or – strategies in critically ill patients and surgical patients.
The role of the European Society of Anaesthesiology and Intensive Care is to support and facilitate meetings and communication between Research Groups.
Mission of PROVENet
The mission of the PROVE Network is to test novel mechanical ventilation strategies and – devices, as well as non–ventilatory supplemental strategies and –devices to improve the care and safety of patients who need mechanical ventilation, including those in emergency units, intensive care units and operating rooms.
Website of PROVENet www.provenet.eu
Contact Person of PROVENet : research@esaic.org
Marcus J. Schultz (Amsterdam, The Netherlands) |
Sabrine N.T. Hemmes (Amsterdam, The Netherlands) |
Marcelo Gama de Abreu (Dresden, Germany) |
Ary Serpa Neto (SĂŁo Paulo, Brazil) |
- Title: PROtective VENTilation during THORAX surgery
- Aim: To determine whether a strategy with higher PEEP plus recruitment manoeuvres improves clinical outcome in patients receiving one-lung ventilation
- Design: International multicenter double-blind randomized controlled two-arm trialÂ
- Population: Patients planned for thoracic surgery with one-lung ventilation
- Status: Recruiting patients, Call for participating centres
- Trial site:Â http://prothor.info
- Clinicaltrials.gov:Â https://clinicaltrials.gov/ct2/show/NCT02963025
Join the largest study on intraoperative mechanical ventilation ever and become a collaborative co-author!
- Email:Â prothor@peg-dresden.de
Project of PROVENet endorsed by ESAIC: PROBESE
- Title: PRotective ventilation of OBESE patients
- Aim: To determine whether a strategy with higher PEEP (12 cmH2O) plus recruitment manoeuvres improves clinical outcome in obese patients (BMI >=35) receiving mechanical ventilation during general anaesthesia for surgery
- Design:Â International multicenter double-blind randomized controlled two-arm trial
- Population:Â Obese patients (BMI >=35) undergoing surgery under general anaesthesia with a duration of longer >2 hours
- Status:Â Study has reached Recruitment Target
- Trial site:Â www.peg-dresden.de/probese
- Clinicaltrials.gov:Â Description of study details
- Email:Â probese@peg-dresden.de