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The study has been published!

The POSE-Trial Research Group aimed to describe the 30-day mortality of patients aged 80 years and older undergoing surgical and nonsurgical procedures under anaesthesia in Europe and to identify risk factors associated with mortality.

POSE was able to include data from 9497 patients from 177 hospitals in 20 countries. This is a great success from the ESAIC POSE-Trial RG and would not have been possible without the exceptional support from the POSE-Study group! Please find below the link to the EJA Open Access publication of the main analysis and the first subgroup analysis.

  • POSE-Study group. Peri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study. Eur J Anaesthesiol 202; doi: 10.1097/EJA.0000000000001639. Online ahead of print.
  • Ana Kowark, Moritz Berger, Rolf Rossaint, Matthias Schmid, Mark Coburn, POSE-Study group. Association between benzodiazepine premedication and 30-day mortality rate: A propensity-score weighted analysis of the Peri-interventional Outcome Study in the Elderly (POSE). Eur J Anaesthesiol 2021; doi: 10.1097/EJA.0000000000001638. Online ahead of print.


Primary: To determine the peri-interventional (surgical and non-surgical interventional) all-cause mortality rate on day 30.

Secondary: To assess an array of post-interventional major complications and functional and cognitive outcomes until the post-interventional day 30.

Study design

European multi-centre, prospective observational cohort study with the aim to Include 7500 patients in total.
Recruitment period: 30 days (self-selected by each centre)

Follow-up period per patient: 30 days after intervention

Inclusion criteria

  1. Age ≥ 80 years
  2. Written informed consent prior to study participation
  3. All consecutive patients undergoing surgical and non-surgical interventions (e.g. radiological, neuroradiological, cardiological, gastroenterological) with anaesthesia care (performed by an anaesthetist) within the selected inclusion period of 30 days
  4. Elective and emergency procedures
  5. In-patient and out-patient procedures

Exclusion criteria

  1. People who are institutionalized by court or administrative order
  2. Patients with re-intervention within the 30 days recruitment period, who were already enrolled in this study

Website POSE


Contact Person

Mark Coburn (University Hospital RWTH Aachen):           mcoburn@ukaachen.de
Ana Kowark (University Hospital RWTH Aachen):             akowark@ukaachen.de