Data collection for SQUEEZE has been postponed for all centres to October 2020

Some countries are ready to start from October 2020 :
Greece 05/10/2020, Sweden 05/10/2020, Slovenia 06/10/2020, Morocco 12/10/2020, Australia 19/10/2020, Bulgaria 19/10/2020, Canada 19/10/2020, Netherlands 27/10/2020, Denmark 20/10/2020, Germany 09/11/2020, Iceland 18/01/2021, United Kingdom Mid-January 2021

Chief Investigators

  • Dr. Ib JAMMER (Haukeland University Hospital – Bergen, Norway)
  • Dr. Ben Creagh-Brown (Royal Surrey County Hospital NHS Foundation Trust – Guildford
    d, United Kingdom)

Steering Committee

Lui Forni (UK), Ramani Moonesinghe (UK) and Hannah Wunsch (Canada), Anil Gupta (Sweden), Peter Martin (UK).

The ESAIC Secretariat and Steering Committee are looking for National Coordinating Investigator to support the conduction of SQUEEZE study, if you are interested, please contact us at


The Study is entirely sponsored by a grant from the European Society of Anaesthesiology Clinical Trial Network (ESAIC CTN). The aim of the European Society of Anaesthesiology Clinical Trial Network is to provide an infrastructure for clinical research in the fields of Anaesthesia, Pain, Intensive Care and Emergency Medicine by transnational European collaborative studies.

The study is endorsed by the European Society of Intensive Care Medicine (ESICM).

Participating Countries


  • To evaluate the proportion of non-cardiac surgical patients receiving postoperative vasopressors.
  • To evaluate the characteristics of patients, surgery and anaesthesia that lead to postoperative vasopressor use.
  • To evaluate the incidence of organ injury in patients who receive postoperative vasopressors
  • To evaluate the variability in postoperative vasopressor use across healthcare environments.

Medical Problem

In the era of goal-directed fluid therapy and increasing popularity of restrictive fluid resuscitation, patients may be receiving less intravenous fluid and receiving more infused vasopressors to maintain adequate blood pressure.

There is anecdotal evidence of substantial variation in the management of post-operative hypotension between centres, countries and continents. The variation is in assessment (cardiac output and invasive monitoring) and environment (post-operative care units, high-dependency units, ICUs) and management (use and choice of fluids and vasopressors/inotropes).

In critically ill populations, receipt of infused vasopressors is associated with organ dysfunction, it has not been established if this relationship is true in postoperative populations.

Outcome Measures

  • Incidence of vasopressor use, and elucidation of risk factors
  • Postoperative organ dysfunction in patients receiving infused vasopressors.


  • Study selected by ESAIC Research Committee: April 2018
  • Call for centres: Ongoing

Join the study

This study will recruit as many participating institutions as possible across the 30 European countries represented at the ESAIC Council. It is plan to recruit at least 40,000 patients.

Would your hospital like to join this study as an actively contributing research centre? The ‘Call for Centres form’ must be filled in online. The completion of this form will facilitate the coordination and is mandatory for participation in ESAIC CTN. ESAIC Secretariat will then contact you providing you with additional information.

Please visit the call for centres page.

Contact us

European Society of Anaesthesiology

Rue des Comédiens 24
1000 Brussels, Belgium
T: +32 2 743 32 94 / +32 2 210 94 14
F: +32 2 743 32 98